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1.
1394 Accesses
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Inhibition of microRNA function by antimiR oligonucleotides
Jan Stenvang, Andreas Petri, Morten Lindow, Susanna Obad, Sakari Kauppinen Silence 2012, 3:1 (9 January 2012)
Abstract | Provisional PDF
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2.
415 Accesses
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Experimental design, preprocessing, normalization and differential expression analysis of small RNA sequencing experiments
Kevin P McCormick, Matthew R Willmann, Blake C Meyers Silence 2011, 2:2 (28 February 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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3.
376 Accesses
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microRNA as a new immune-regulatory agent in breast milk
Nobuyoshi Kosaka, Hirohisa Izumi, Kazunori Sekine, Takahiro Ochiya Silence 2010, 1:7 (1 March 2010)
Abstract | Full text | PDF | PubMed
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4.
353 Accesses
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A status report on RNAi therapeutics
Akshay K Vaishnaw, Jared Gollob, Christina Gamba-Vitalo, Renta Hutabarat, Dinah Sah, Rachel Meyers, Tony de Fougerolles, John Maraganore Silence 2010, 1:14 (8 July 2010)
Abstract | Full text | PDF | PubMed
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5.
318 Accesses
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Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2
Nikolaus Schultz, Dina R Marenstein, Dino A De Angelis, Wei-Qing Wang, Sven Nelander, Anders Jacobsen, Debora S Marks, Joan Massagué, Chris Sander Silence 2011, 2:3 (14 March 2011)
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6.
308 Accesses
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How do miRNAs mediate translational repression?
Shuo Gu, Mark A Kay Silence 2010, 1:11 (7 May 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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7.
279 Accesses
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Aptamer-targeted cell-specific RNA interference
Jiehua Zhou, John J Rossi Silence 2010, 1:4 (1 February 2010)
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8.
249 Accesses
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Helicobacter pylori interferes with an embryonic stem cell micro RNA cluster to block cell cycle progression
Cédric Belair, Jessica Baud, Sandrine Chabas, Cynthia M Sharma, Jörg Vogel, Cathy Staedel, Fabien Darfeuille Silence 2011, 2:7 (25 October 2011)
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9.
243 Accesses
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MicroR159 regulation of most conserved targets in Arabidopsis has negligible phenotypic effects
Robert S Allen, Junyan Li, Maria M Alonso-Peral, Rosemary G White, Frank Gubler, Anthony A Millar Silence 2010, 1:18 (28 October 2010)
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10.
241 Accesses
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Development of the human cancer microRNA network
Sanghamitra Bandyopadhyay, Ramkrishna Mitra, Ujjwal Maulik, Michael Q Zhang Silence 2010, 1:6 (2 February 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Cancer-microRNA network elucidates the association between miRNAs and cancer types. The network indicates neighboring miRNAs are differentially co-expressed, and could be used to detect miRNAs with strong onco/ tumor suppressor characteristics.
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11.
231 Accesses
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Effect of small interfering RNA 3'-end overhangs on chemosensitivity to thymidylate synthase inhibitors
John C Schmitz, Edward Chu Silence 2011, 2:1 (19 January 2011)
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12.
208 Accesses
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Noncoding RNA localisation mechanisms in chromatin regulation
Aditi Kanhere, Richard G Jenner Silence 2012, 3:2 (31 January 2012)
Abstract | Provisional PDF
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13.
195 Accesses
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Posttranslational modification of Argonautes and their role in small RNA-mediated gene regulation
Michael Johnston, Gyorgy Hutvagner Silence 2011, 2:5 (26 September 2011)
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14.
182 Accesses
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Specificity and functionality of microRNA inhibitors
Barbara Robertson, Andrew B Dalby, Jon Karpilow, Anastasia Khvorova, Devin Leake, Annaleen Vermeulen Silence 2010, 1:10 (1 April 2010)
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15.
173 Accesses
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The dose can make the poison: lessons learned from adverse in vivo toxicities caused by RNAi overexpression
Dirk Grimm Silence 2011, 2:8 (26 October 2011)
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16.
172 Accesses
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RNA silencing in plants: Flash report!
Rebecca A Mosher, Mathew G Lewsey, Padubidri V Shivaprasad Silence 2010, 1:13 (30 June 2010)
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17.
170 Accesses
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A 5′-uridine amplifies miRNA/miRNA* asymmetry in Drosophila by promoting RNA-induced silencing complex formation
Hervé Seitz, Jogender S Tushir, Phillip D Zamore Silence 2011, 2:4 (7 June 2011)
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18.
160 Accesses
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Naturally occurring variations in sequence length creates microRNA isoforms that differ in argonaute effector complex specificity
H Alexander Ebhardt, Amber Fedynak, Richard P Fahlman Silence 2010, 1:12 (9 June 2010)
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19.
157 Accesses
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Noncoding RNAs and cancer
Ohad Yogev, Dimitris Lagos Silence 2011, 2:6 (29 September 2011)
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20.
148 Accesses
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An endogenous F-box protein regulates ARGONAUTE1 in Arabidopsis thaliana
K Earley, MR Smith, R Weber, BD Gregory, RS Poethig Silence 2010, 1:15 (12 July 2010)
Abstract | Full text | PDF | PubMed
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Editor’s summary
An endogenous F-box protein negatively regulates the protein levels of ARGONAUTE1, a core component of the RNA-induced silencing complex, and affects the sensitivity of plants to the growth regulator abscisic acid.
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21.
148 Accesses
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How to slice: snapshots of Argonaute in action
James S Parker Silence 2010, 1:3 (12 January 2010)
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22.
125 Accesses
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Expression patterns of intronic microRNAs in Caenorhabditis elegans
Meltem Isik, Hendrik C Korswagen, Eugene Berezikov Silence 2010, 1:5 (1 February 2010)
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23.
123 Accesses
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Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent
Genhua Zheng, Victor Ambros, Wen-hong Li Silence 2010, 1:9 (1 April 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology
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Editor’s summary
Dextran was conjugated with 2'-O-methyl oligoribonucleotides to develop fluorescently labeled antisense reagents, which were introduced to the germ line of adult hermaphrodite Caenorhabditis elegans, and caused specific miRNA inhibition in different tissues in the embryonic and larval development of the progeny.
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24.
110 Accesses
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A structural-based statistical approach suggests a cooperative activity of PUM1 and miR-410 in human 3'-untranslated regions
Limor Leibovich, Yael Mandel-Gutfreund, Zohar Yakhini Silence 2010, 1:17 (22 September 2010)
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25.
105 Accesses
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Solution structure of the Drosha double-stranded RNA-binding domain
Geoffrey A Mueller, Matthew T Miller, Eugene F DeRose, Mahua Ghosh, Robert E London, Traci Hall Silence 2010, 1:2 (12 January 2010)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Structural studies of Drosha, a nuclear RNAse III enzyme, which in complex with DGCR8 initiates processing of miRNAs, reveal that the Drosha-dsRBD retains RNA-binding features, and may contribute to substrate recognition.
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