Table 3

Nine factors for linear regression

Factor

Description

Values

ln3

Target's 3' UTR length

0~1

cs3

Target's overall 3' UTR conservation

0~1

exp

Target's mRNA expression level as measured by RNA-Seq.

0~1

#site_m

The number of miRNA or siRNA target sites in the target's 3' UTR

0~1

#endo_m

The number of target sites for endogenous miRNAs in the target's 3' UTR

0~1

#site_s

The total number of miRNA or siRNA target sites in all the potential target 3' UTRs

0~1

p_ma

Binary variable stating whether the target's fold change was measured by microarray or proteomics

1: Microarray

0: Proteomics

e_oe

Binary variable stating whether the target's fold change was measured after miRNA transfection or inhibition

1: Transfection

0: Inhibition

ts_score

mRNA level TargetScan scores. Only used in the last regression model.

0~1

All values are either in a range between 0 and 1 (0~1) or binary (0 or 1). miRNA, microRNA; mRNA, messenger RNA; siRNA, small interfering RNA; UTR, untranslated region.

Saito and Sætrom Silence 2012 3:3   doi:10.1186/1758-907X-3-3