Silence


Open Access Short report

Naturally occurring variations in sequence length creates microRNA isoforms that differ in argonaute effector complex specificity

H Alexander Ebhardt, Amber Fedynak and Richard P Fahlman*

Author Affiliations

Department of Biochemistry, School of Molecular and Systems Medicine, University of Alberta, Edmonton, T6G 2H7, Canada

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Silence 2010, 1:12 doi:10.1186/1758-907X-1-12

Published: 9 June 2010

Additional files

Additional file 1:

Validation of computer-generated miRNA isoforms. An in silico northern blot was performed of all computer-generated miRNA isoforms by scanning seven different datasets for the expression of each in silico miRNA isoform.

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Open Data

Additional file 2:

Validated miRNA isoforms and their AGO association. All validated miRNA isoforms from Additional file 1 were scanned across various argonaute complexes.

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Open Data