Table 1

Examples showing alignment of mature sequences from miR-15 family members and non-family member with matching seeds

Family member

miRNA name

Mature sequence from 5' to 3' end

Family members with sequence identity in both the seed region^a and the 3' region^b

hsa-miR-15a^c

UAGCAGCACAUAAUGGUUUGUG

| | | | | | | | | | | | | | | | | |   

hsa-miR-15b^c

UAGCAGCACAUCAUGGUUUACA

Family members with sequence identity in the seed region^a but very limited identity in the 3' region^b

hsa-miR-15a^c

UAGCAGCACAUAAUGGUUUGUG

| | | | | | | | | | | |   | | | |

hsa-miR-16^c

UAGCAGCACGUAAAUAUUGGCG

Non-family members with sequence identity both in the seed region^a and in the 3' region^b

hsa-miR-15a^c

UAGCAGCACAUAAUGGUUUGUG

 | | | | | | | | |   | | | | | | | | 

hsa-miR-497^d

CAGCAGCACACUGUGGUUUGU 

^aBold and italicised.

^bBold.

^cMember of the miR-15 family.

^dMember of the miR-497 family.

Robertson et al. Silence 2010 1:10   doi:10.1186/1758-907X-1-10